Article list

Fast 3D magnetic field mapping using MRSI with circular sampling for 31P applications

Investigators: Ladislav Valkovič, Pavol Szomolányi Quantifying the concentration of energy metabolites requires accurate measurement of the magnetic field (B1), especially at 7T where the excitation coils face large field inhomogeneities. Measuring the B1 field using standard signal sampling is relatively time-consuming. It takes about 40 minutes to cover the entire heart, which is too long…

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Method for quantifying intramuscular phosphocreatine (PCr) depletion and recovery using ³¹P MRS and the behavior of the creatine CH₂ signal in ¹H MRS

Investigator: Radka Klepochová In this work, we focused on obtaining information about two key processes at the same time: the depletion and recovery of intramuscular phosphocreatine (PCr) using ³¹P MRS and the behavior of the creatine CH₂ signal in ¹H MRS, which exhibits similar dynamics. While previous studies required separate ¹H and ³¹P measurements with…

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Eficient computational methods for the characterization of the materials at the nanoscale

Investigators: Viktor Witkovský (ÚM SAV), Gejza Wimmer (MÚ SAV), Anna Charvátová Campbell (ČMI), Petr Klapetek (ČMI), Radek Šlesinger (ČMI) As part of the international bilateral SK-CZ project, we designed and implemented efficient computational methods for evaluating the mechanical properties of materials at the nanoscale using instrumented indentation (IIT) and atomic force microscopy (AFM). The OEFPIL…

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Wearable smart patch for monitoring vital functions in life support system

Investigators: Milan Tyšler, Richard Bagín, Daniel Gogola, Fedor Lehocki, Beáta Ondrušová An innovative system for monitoring the vital functions of injured persons during mass disasters was developed. The system features smart patches designed to record electrocardiograms, photoplethysmograms, respiratory movements, and body temperature from the chest of injured persons. The patches autonomously evaluate heart rate and…

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Comparison of dipole-based and potential-based ECGI methods for premature ventricular contraction beat localization with clinical data

Investigators: Švehlíková J., Ondrušová B., Zelinka J., Tyšler M., Hlivák P., Rasoolzadeh N., Serinagaoglu-Dogrusoz Y.S., The aim of the joint project of the IOM SAS and Middle East University in Ankara was to apply the inverse electrocardiography methods used at each site to the same data from multi-lead chest measurements. We applied the inverse methods…

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Assessment of cardiac and skeletal muscle energy metabolism in clinical trials for efficacy of treatments for patients with heart failure, or long COVID patients

Investigator: Ladislav Valkovič, Ústav merania, v. v. i., SAV Our non-invasive methods for energy metabolism assessment using phosphorus MR spectrscopy are ideal for treatment testing in patients, where cardaic or skeletal muscle metabolism is impaired. Hence in collaboration with Boeringer Ingelheim, we have tested the potential mecahnism of effect of their new sodium-glucose co-transporter inhibitor…

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Advances in numerical methods and algorithms for the computation of complex probability distributions in uncertainty analysis of measurement results

Investigators: Viktor WITKOVSKÝ, Laura HAJZOKOVÁ , IMS SAS + foreign partners In 2023, our collaboration with researchers from the University of Montenegro contributed to advances in probabilistic modelling and numerical methods and algorithms for the computation of complex probability distributions, which are often encountered in the analysis of uncertainties in measurement results in various application…

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