Article list

Optimized 3D imaging of biological objects by X-ray microtomography methods

Optimized X-ray microtomographic methodologies of three-dimensional visualization of biological objects and their internal microstructures were developed. Optimization of microtomographic measurements for a specific object included the choice of target material, optimized acceleration voltage and X-ray tube current, signal accumulation time on the detector, number of repetitions, choice of relaxation time between two measurements and number…

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Clustering of symptoms of intracranial pressure time series for estimation of alarm function in traumatic brain injuries

Investigators: M. Teplan, I. Bajla, R. Rosipal) When monitoring patients with severe head injury, the so-called method is used in clinical practice. critical value of the intracranial pressure time course (VLT). Exceeding this threshold is evaluated as an alarm situation, on the basis of which the medical staff initiates an emergency procedure (protocol) to save…

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Biodegradable magnetic polymer nanocomposite based on natural nanotubes

(Investigator: M. Škrátek) Biodegradable polymer nanocomposites represent a promising group of plastics usable for various bio- and enviro-friendly applications, such as drug carriers or biological plastics with shape memory. Polymers are generally electrically non-conductive and non-magnetic materials. Natural Halloyzite nanotubes (HNT) modified with iron oxide nanoparticles were used to improve the mechanical properties of the…

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New methods for determination of oxidative metabolism of skeletal muscle using phosphorus MR saturation transfer at rest and during exercise

(Investigators: L. Valkovič, I. Frollo) Cardiovascular disease, obesity and diabetes are very often accompanied by changes in the energy metabolism of skeletal muscle. Therefore, modern medicine is placing increasing emphasis on research into new non-invasive methods for measuring energy metabolism. In line with this trend, new methodologies for determining oxidative metabolism using static and dynamic…

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