Article list

Investigators: Valkovič L.  Frollo, I.  Ústav merania SAV Phosphorous MR spectroscopy (31P-MRS) forms a powerful, non-invasive research tool for energy metabolism quantification in the heart and skeletal muscle tissue in diverse patient populations.  In this work, we have quantitatively assessed the impact of contrast agents, used in radiology, on the relaxation properties of 31P metabolites….

Advanced high-resolution X-ray microtomography measurement methods have been developed in evolutionary biology (team led by Prof. Klembar, PriF UK) and helped solve the more than 100-year-old problem concerning the origin of amniotics and thus the important stage of vertebrate evolution. Fossil findings of two groups of early quadrupeds and amniotic progenitors (Diadectomorph and Seymouriamorph) were…

Investigators: Svehlikova, J. – Zelinka, J. – Tysler M. – Tino, P. In an informal collaboration with P. Tín from the University of Birmingham, we investigated the possibility of using two parameters simultaneously for non-invasive inverse localization of the stimulation site in a patient with stimulated heart activity using surface ECG maps and chest geometry…

Investigators: Anna Krakovská, Jozef Jakubík   Methods of causal analysis have been applied in diverse scientific fields from economics, through climate sciences to research trying to understand connections in the human brain. We already know that time series from dynamical systems require different approaches than, for example, causal analysis of interconnected autoregressive processes. In [1]…

Investigators: R. Rosipal, N. Porubcová, Z. Rošťáková Mirror therapy is a new tool for the rehabilitation of damaged motor pathways and functions of patients after a stroke. It is based on visual feedback imitating the movement of the injured limb. In the study we have shown that mirror therapy is associated with prolonged changes in…

Investigator: M. Majerová   Aluminate glasses are interesting in terms of their basic structure. The main net forming element is aluminum, while in conventional glasses it is e.g. silicon. Aluminate glasses have excellent mechanical properties, excellent corrosion resistance, show better light and heat resistance and better light conductivity than common silicate glasses. Another important property…

Investigator: L. Valkovič Failing heart is like a pump without fuel; where besides depletion in energy rich metabolites tissue often undergoes acidification. Measurement of intra-myocardial pH using typical magnetic resonance methods hindered by the dominant signal originating in blood that obscures inorganic phosphate (Pi) signal. We have therefore developed a new method using long repetition…

Investigators: Švehlíková, E. Cocherová, J. Zelinka, M. Haška, M. Tyšler The activation of heart ventricles during right ventricular pacing was simulated in realistic patient heart geometry using activation models based on cellular automaton (CA) and reaction-diffusion equations (RD). Using the RD model, also normal ventricular activation was simulated that visually matched with the published experimental…

Investigators: J. Švehlíková, M. Teplan, M. Tyšler In the simulation study, we solved the inverse task of ECG electrocardiography in order to evaluate the possibility of localization of premature ventricular activity (PCA) simulated at 8 different points in a realistic model of the ventricles. We used simulated data provided by the Institute of Biomedical Engineering…

(Investigators: A. Krakovská, M. Chvosteková, J. Jakubík) Causal analysis of large volumes of measured data is becoming a hot topic of research. Existing techniques have been shown to be insufficient and their non-critical use often leads to completely incorrect conclusions. We have been working intensively on this topic for several years. We test existing methods…