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New methods of ensuring homogeneous signal excitation for determination of energy metabolism of skeletal muscles, liver and heart on 7T MRI tomography

(Investigators: L. Valkovič, I. Frollo) Phosphorus MR spectroscopy (31P-MRS) is a unique technique that allows non-invasive measurement of tissue energy metabolism in vivo. However, due to the low signal-to-noise ratio (SNR), it is still not commonly used in medical practice. MR systems with a magnetic field strength of 7T in combination with surface coils achieve…

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New methods for determination of oxidative metabolism of skeletal muscle using phosphorus MR saturation transfer at rest and during exercise

(Investigators: L. Valkovič, I. Frollo) Cardiovascular disease, obesity and diabetes are very often accompanied by changes in the energy metabolism of skeletal muscle. Therefore, modern medicine is placing increasing emphasis on research into new non-invasive methods for measuring energy metabolism. In line with this trend, new methodologies for determining oxidative metabolism using static and dynamic…

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