Comparison of dipole-based and potential-based ECGI methods for premature ventricular contraction beat localization with clinical data

Investigators: Švehlíková J., Ondrušová B., Zelinka J., Tyšler M., Hlivák P., Rasoolzadeh N., Serinagaoglu-Dogrusoz Y.S.,

The aim of the joint project of the IOM SAS and Middle East University in Ankara was to apply the inverse electrocardiography methods used at each site to the same data from multi-lead chest measurements. We applied the inverse methods to realistic ECG measurements of patients with premature ventricular activity (PKA) performed in collaboration with the National Institute of Cardiac and Vascular Diseases in Bratislava, also to data from an available database. We compared the results of the localization of the area of PKA onset calculated both by using a simple dipole and also by calculating the so-called activation time on the heart from the potentials on the cardiac surface. We calculated the localization error (LE) between the obtained inversion problem result and the site of invasive inactivation of the PKA origin, which was marked by the cardiologist who performed the procedure. Results from the database and measurements showed the stability and greater accuracy of the dipole method (LE = 25,28,30mm) compared to the potential method (LE = 23,38,31mm). The localization of PKA may contribute to reduce the procedure time required for its removal.

Related project: JRP SAV-TUBITAK 536057

Publications:

• DOGRUSOZ, Y.S.** – RASOOLZADEH, N. – ONDRUŠOVÁ, Beáta – HLIVAK, P. – ZELINKA, Ján – TYŠLER, Milan – ŠVEHLÍKOVÁ, Jana. Comparison of dipole-based and potential-based ECGI methods for premature ventricular contraction beat localization with clinical data. In Frontiers in Physiology, 2023, vol. 14, art. no. 1197778. (2022: 4 – IF, Q2 – JCR, 1.028 – SJR, Q1 – SJR). ISSN 1664-042X. Dostupné na: https://doi.org/10.3389/fphys.2023.1197778  (VEGA č. 2/0109/22: Use of multi-lead ECG measurement and modeling of the electric field of the heart in non-invasive diagnostics and therapy of ventricular arrhythmias and heart failure. APVV-19-0531: Personalized optimisation of cardiac resynchronization therapy in heart failure based on multiple lead ECG measurement)
• RASOOLZADEH, N. – ONDRUŠOVÁ, Beáta – DOGRUSOZ, Y.S. – ŠVEHLÍKOVÁ, Jana. Effects of torso inhomogeneities on spontaneous PVC localization in potential and dipole-based methods. In Proceedings of the 14th International Conference on Measurement. – Bratislava: Institute of Measurement Science, SAS, 2023, p. 2-5. ISBN 978-80-972629-7-6. https://doi.org/10.23919/MEASUREMENT59122.2023.10164347
• Dogrusoz, Y.S., Rasoolzadeh, N., Ondrusova, B., Hlivak, P., Svehlikova, J. (2023). Evaluation of Inverse Electrocardiography Solutions Based on Signal-Averaged Beats to Localize the Origins of Spontaneous Premature Ventricular Contractions in Humans. In: Bernard, O., Clarysse, P., Duchateau, N., Ohayon, J., Viallon, M. (eds) Functional Imaging and Modeling of the Heart. FIMH 2023. Lecture Notes in Computer Science, vol 13958. Springer, Cham. https://doi.org/10.1007/978-3-031-35302-4_17.