Development of methods based on impedance spectroscopy for cell characterization

PhD study program: Measurement Technology
Akademic year: 2022-2023
Advisor: Mgr. Michal Teplan, PhD. (michal.teplan@savba.sk)
External educational institution: Institute of Measurement Science SAS
Accepting university: Faculty of Electrical Engineering and Information Technology, Slovak University of Technology in Bratislava, Institute of Electrical Engineering

Annotation:

The aim of the dissertation is the development of new measurement methods of impedance spectroscopy to characterize the properties of living cells and their growth dynamics. The broader context of the work is research focused on the influence of external weak low-frequency electromagnetic fields on the functions of selected biological objects, with a vision for the development of new diagnostic and therapeutic methods. Part of the work will be the design and implementation of HW, SW and integration of the impedance module into an experimental platform enabling quantitative characterization of the biological response of cells. The aim of the dissertation is to investigate various variants of methods based on impedance spectroscopy, which can be used to determine the concentration of cells in a liquid medium. The candidate is expected to have experience with the design of interfaces for electronic devices and programming knowledge in Matlab. A good knowledge of technical English is mandatory.