Projekt vedeckej grantovej agentúry VEGA č. 2/0013/14

Doba riešenia: 01/2014 - 12/2016

Zameranie projektu

 Podstatou projektu je základný výskum vybraných zobrazovacích metód na báze NMR - zobrazovania, merania a mapovania špecifických fyzikálnych veličín organických a syntetických materiálov a objektov v oblasti rozvoja materiálového a biomedicínskeho výskumu.

Zameranie projektu:

1. Teoretický a experimentálny výskum metód merania a mapovania vlastností špecifických fyzikálnych veličín organických a syntetických materiálov a objektov.

2. Detekcia homeostázy železa v organizme, magnetické vlastnosti železitých komplexov.

3. Sledovanie procesu dozrievania chrupavky ľudských končatín v období nasledujúcom po transplantácii chrupavky. Algoritmy na spracovanie relaxačných časov.

4. Zobrazovanie resyntézy fosfokreatínu po záťaži pomocou MRI a MRSI.

5. Štúdium spektrálnych vlastností vibrácií v MR tomografe, vývoj algoritmu na potláčanie ich vplyvu.

6. Teoretické modely dynamiky pohybu sférických kvapiek aerosólu z magnetických nanočastíc pľúcneho alveolu v gradientných magnetických poliach.

Vybrané publikácie:

2014

1. ANDRIS, Peter - JACKO, Vlado - DERMEK, Tomáš - FROLLO, Ivan. Noise measurement of a preamplifier with high input impedance using an NMR console. In Measurement, 2014, vol. 55, p. 408-412. ISSN 0263-2241. (1.526-IF2013)
2. JURÁŠ, Vladimír - APPRICH, S. - ZBÝŇ, Š. - ZAK, L. - DELIGIANNI, X. - SZOMOLÁNYI, P. - BIERI, O. - TRATTNIG, S. Quantitative MRI analysis of menisci using biexponential T2* fitting with a variable echo time sequence. In Magnetic Resonance in Medicine, 2014, vol. 71, no. 3, p. 1015-1023. ISSN 0740-3194. (3.398-IF2013)
3. ŠTRBÁK, Oliver - KRAFČÍK, Andrej - TEPLAN, Michal - GOGOLA, Daniel - KOPČANSKÝ, P. - FROLLO, Ivan. Biogenic magnetite nanoparticle ensemble use in MRI diagnostics. In Acta Physica Polonica A, 2014, vol. 126, no. 1, p. 388-389. ISSN 0587-4246. (0.604-IF2013)
4. VALKOVIČ, Ladislav - GAJDOŠÍK, M. - TRAUSSNIGG, S. - WOLF, P. - CHMELÍK, M. - KIENBACHER, Ch. - BOGNER, W. - KREBS, M. - TRAUNER, M. - TRATTNIG, S. - KRŠŠÁK, M. Application of localized 31P MRS saturation transfer at 7 T for measurement of ATP metabolism in the liver: Reproducibility and initial clinical application in patients with non-alcoholic fatty liver disease. In European Radiology, 2014, Vol. 24, no. 7, p. 1602-1609. ISSN 0938-7994. (4.338-IF2013)
5. VALKOVIČ, Ladislav - CHMELÍK, M. - KUKUROVÁ, I.J. - JAKUBOVÁ, M. - KIPFELSBERGER, M.Ch. - KRUMPOLEC, P. - JELENC, M.T. - BOGNER, W. - MEYERSPEER, M. - UKROPEC, J. - FROLLO, Ivan - UKROPCOVÁ, B. - TRATTNIG, S. - KRŠŠÁK, M. Depth-resolved surface coil MRS (DRESS)-localized dynamic 31P-MRS of the exercising human gastrocnemius muscle at 7 T. In NMR in Biomedicine, 2014, vol. 27, no. 11, p. 1346-1352. ISSN 0952-3480. (3.559-IF2013)
6. VALKOVIČ, Ladislav - BOGNER, W. - GAJDOŠÍK, M. - POVAŽAN, M. - KUKUROVÁ, I.J. - KRŠŠÁK, M. - GRUBER, S. - FROLLO, Ivan - TRATTNIG, S. - CHMELÍK, M. One-dimensional image-selected in vivo spectroscopy localized phosphorus saturation transfer at 7T. In Magnetic Resonance in Medicine, 2014, vol. 72, no. 6, p. 1509-1515. ISSN 0740-3194. (3.398-IF2013) 

2015

1. FROLLO, Ivan - KRAFČÍK, Andrej - ANDRIS, Peter - PŘIBIL, Jiří - DERMEK, Tomáš. Circular Samples as Objects for Magnetic Resonance Imaging - Mathematical Simulation, Experimental Results. In Measurement Science Review, Volume 15, No. 6, 2015, p. 313-318. ISSN 1335 - 8871. (0.989-IF2014)
2. ŠTRBÁK, Oliver - MASÁROVÁ, Marta - GOGOLA, Daniel - SZOMOLÁNYI, Pavol - FROLLO, Ivan. Influence of saline and glucose molecules to contrast properties of clinically used MRI contrast agents. In Measurement, 2015, vol. 69, p. 109-114. ISSN 0263-2241. (1.484-IF2014)
3. KRAFČÍK, Andrej - BABINEC, P. - FROLLO, Ivan. Computational analysis of magnetic field induced deposition of magnetic particles in lung alveolus in comparison to deposition produced with viscous drag and gravitational force. In Journal of Magnetism and Magnetic Materials, 2015, vol. 380, p. 46-53. ISSN 0304-8853. (1.970-IF2014)
4. GOGOLA, Daniel - ŠTRBÁK, Oliver - KRAFČÍK, Andrej - ŠKRÁTEK, Martin - FROLLO, Ivan. Magnetic resonance imaging of the static magnetic field distortion caused by magnetic nanoparticles: Simulation and experimental verification. In Journal of Magnetism and Magnetic Materials, 2015, vol. 380, p. 261-265. ISSN 0304-8853. (1.970-IF2014)
5. JURÁŠ, Vladimír - WINHOFER, Y. - SZOMOLÁNYI, Pavol - VOSSHENRICH, J. - HAGER, B. - WOLF, P. - WEBER, M. - LUGER, A. - TRATTNIG, S. Multiparametric MR imaging depicts glycosaminoglycan change in the Achilles tendon during ciprofloxacin administration in healthy men: Initial observation. In Radiology, 2015, vol. 275, no. 3, p. 763-771. ISSN 0033-8419. (6.867-IF2014)

2016

1. ANDRIS, Peter - FROLLO, Ivan. Noise and interference in measured NMR images. In Measurement, 2016, vol. 77, p. 29-33. ISSN 0263-2241. (1.742-IF2015)

2. JURÁŠ, Vladimír - ZBÝŇ, Š. - MLYNÁRIK, V. - SZOMOLÁNYI, Pavol - HAGER, B. - BAER, P. - FROLLO, Ivan - TRATTNIG, S. The compositional difference between ankle and knee cartilage demonstrated by T2 mapping at 7 Tesla MR. In European Journal of Radiology, 2016, vol. 85, no. 4, p. 771-777. ISSN 0720-048X. (2.593-IF2015)

3. PŘIBIL, Jiří - PŘIBILOVÁ, A. - FROLLO, Ivan. Comparison of mechanical vibration and acoustic noise in the open-air MRI. In Applied Acoustics, 2016, vol. 105, p. 13-23. ISSN 0003-682X. (1.462-IF2015)

4. ŠTRBÁK, Oliver - KANUCHOVÁ, Z. - KRAFČÍK, Andrej. Proton gradients as a key physical factor in the evolution of the forced transport mechanism across the lipid membrane. In Origins of Life and Evolution of Biospheres, 2016, vol. 46, no. 4, p. 523-531. ISSN 0169-6149. (1.141-IF2015)

5. VALKOVIČ, Ladislav - CHMELÍK, M. - UKROPCOVÁ, B. - HECKMANN, T. - BOGNER, W. - FROLLO, Ivan - TSCHAN, H. - KREBS, M. - BACHL, N. - UKROPEC, J. - TRATTNIG S. - KRŠŠÁK, M. Skeletal muscle alkaline Pi pool is decreased in overweight-to-obese sedentary subjects and relates to mitochondrial capacity and phosphodiester content. In Scientific Reports, 2016, vol. 6, p. 20087. ISSN 2045-2322. (5.228-IF2015)