Medziústavná dohoda

Doba riešenia: 08/2006 - 12/2016

Anglický názov: Diagnostics of human articular cartilage using MRI

Vedúci projektu: prof. Ing. Ivan Frollo, DrSc.

Spoluriešiteľské inštitúcie: MR Centre of Excellence, Department of Radiology, Medical University of Vienna. Zmluva o vedeckej spolupráci, Univ.-Prof. Dr. Siegfried Trattnig.

1. Diagnostika ľudských kĺbových chrupaviek za použitia metód zobrazovania na princípe magnetickej rezonancie (MRI).

2. Zobrazovanie mikro- a nanoštruktúr na báze magnetickej rezonancie pre biomedicínsky a materiálový výskum.

3. Vzájomné návštevy vedcov a PhD študentov umožňujúce vykonávať zobrazovacie experimenty na MRI zariadeniach v laboratóriách partnerov v primeraných časových limitoch.

Publikácie v roku 2011:

1. JURÁŠ, Vladimír - WELSCH, G. - BÄR, P. - KRONNERWETTER, C. - FUJITA, H. - TRATTNIG, S. Comparison of 3 T and 7 T MRI clinical sequences for ankle imaging. In European Journal of Radiology, 2011, DOI:10.1016/ j.ejrad.2011.05.023. ISSN 0720-048X. (2.941-IF2010).
2. MAYERHOEFER, M.E. - MAMISCH, T.C. - RIEGLER, G. - WELSCH, G.H. - DOBROCKY, T. - WEBER, M. - APPRICH, S. - SCHEURECKER, G. - SZOMOLÁNYI, Pavol - PUCHNER, S. - TRATTNIG, S. Gadolinium diethylenetriaminepentaacetate enhancement kinetics in the menisci of asymptomatic subjects: a first step towards a dedicated dGEMRIC (delayed gadolinium-enhanced MRI of cartilage)-like protocol for biochemical imaging of the menisci. In NMR in Biomedicine, 2011, DOI:10.1002/nbm.1676. ISSN 0952-3480. (3.064-IF2010)
3. HOCK, A. - VALKOVIČ, Ladislav - FROLLO, Ivan - BOESIGER, P. - HENNING, A. - KOLLIAS, S. Real-time navigator gating in proton liver spectroscopy at 3T. In Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM 2011) : 19th Annual Meeting & Exhibition. Editori D.F. Abbott, J.H. Ackermann et al. - Berkeley, CA, USA : ISMRM, 2011. ISSN 1545-4428, p. 2995. CD-ROM.
4. JURÁŠ, Vladimír - WELSCH, G. - VALKOVIČ, Ladislav - SZOMOLÁNYI, Pavol - NÖBAUER-HUHMANN, I-M. - FROLLO, Ivan - TRATTNIG, S. The comparison of the performance of MRI clinical sequences for ankle imaging at 3T vs 7T. In Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM 2011) : 19th Annual Meeting & Exhibition. Editori D.F. Abbott, J.H. Ackermann et al. - Berkeley, CA, USA : ISMRM, 2011. ISSN 1545-4428, p. 3195. CD-ROM.
5. JURÁŠ, Vladimír - ZBYN, S. - JELLÚŠ, V. - SZOMOLÁNYI, Pavol FROLLO, Ivan - TRATTNIG, S. H relaxation properties of Achilles tendons measured by 3D-UTE at 3T and 7T: a feasibility study. In Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM 2011) : 19th Annual Meeting & Exhibition. Editori D.F. Abbott, J.H. Ackermann et al. - Berkeley, CA, USA : ISMRM, 2011. ISSN 1545-4428, p. 3212. CD-ROM.
6. JURÁŠ, Vladimír - ZBYN, S. - PRESSL, Ch. - SZOMOLÁNYI, Pavol - FROLLO, Ivan - TRATTNIG, S. In vivo measurement of fast transversal relaxation times of achilles tendon using ultra-high field MRI. In MEASUREMENT 2011 : Proceedings of the 8th International Conference on Measurement. Editori J. Maňka, V. Witkovský, M. Tyšler, I. Frollo. - Bratislava : Institute of Measurement Science SAS, 2011. ISBN 978-80-969-672-4-7, p. 352-355.
7. SZOMOLÁNYI, Pavol - PITTSCHIELER, E. - JURÁŠ, Vladimír - FROLLO, Ivan - TRATTNIG, S. Development of dedicated dGEMRIC protocol for biochemical imaging of the temporomandibular joint disc at 3 tesla: A feasibility study. In MEASUREMENT 2011 : Proceedings of the 8th International Conference on Measurement. Editori J. Maňka, V. Witkovský, M. Tyšler, I. Frollo. - Bratislava : Institute of Measurement Science SAS, 2011. ISBN 978-80-969-672-4-7, p. 323-327
8. VALKOVIČ, Ladislav - JURÁŠ, Vladimír - DERMEK, Tomáš - VOJTÍŠEK, Lubomír - FROLLO, Ivan. Low field NMR : The effect of stress on MR image contrast of the human hand. In YBERC 2010 : The 4th Biomedical Engineering Conference of Young Biomedical Engineers and Researches. Editori : Kolektív autorov. - Košice : Technická univerzita v Košiciach, 2011. ISBN 978-80-553-0596-7. CD-ROM.
9. VALKOVIČ, Ladislav - JURÁŠ, Vladimír - GOGOLA, Daniel - VOJTÍŠEK, Lubomír - FROLLO, Ivan. Low-field BOLD effect induced by alcohol and caffeine measured in the upper limb: A feasibility study. In MEASUREMENT 2011 : Proceedings of the 8th International Conference on Measurement. Editori J. Maňka, V. Witkovský, M. Tyšler, I. Frollo. - Bratislava : Institute of Measurement Science SAS, 2011. ISBN 978-80-969-672-4-7, p. 356-359.

2012

1. VALKOVIČ, Ladislav - JURÁŠ, Vladimír - GOGOLA, Daniel - FROLLO, Ivan. The early effect of alcohol and caffeine on a BOLD signal measured in human hand at low-field MRI. In Applied Magnetic Resonance, 2012, vol. 42, no. 4, p. 463-471. ISSN 0937-9347. (0.755-IF2011)

2. JURÁŠ, Vladimír - ZBÝŇ, Š. - PRESSL, Ch. - VALKOVIČ, Ladislav - SZOMOLÁNYI, Pavol - FROLLO, Ivan - TRATTNIG, S. Regional variations of T2* in healthy and pathologic achilles tendon in vivo at 7 Tesla: Preliminary results. In Magnetic Resonance in Medicine, 2012, vol. 68, p. 1607-1613. ISSN 0740-3194. (2.964-IF2011)

3. JURÁŠ, Vladimír - ZBÝŇ, Š. - PRESSL, CH. - DOMAYER, S. - HOFSTAETTER, J. - MAYERHOEFER, M. - WINDHAGER, R. - TRATTNIG, S. Sodium MR imaging of achilles tendinopathy at 7 T: Preliminary results. In Radiology, 2012, vol. 262, no. 1, p. 199-205. ISSN 0033-8419. (5.726-IF2011)

4. JURAS, V., WELSCH, G., BAER, P., KRONNERWETTER, C., FUJITA, H., TRATTNIG, S.: Comparison of 3 T and 7 T MRI clinical sequences for ankle imaging. European Journal of Radiology, vol 81, 2012, pp. 1846-1850. (2.606-IF2011)

5. JURÁŠ, Vladimír - APPRICH, S. - PRESSL, C. - ZBYN, S. - SZOMOLANYI, P. - DOMAYER, S. - FROLLO, Ivan - TRATTNIG, S. Multiparametric MRI assessment of cadaver achilles tendon at 7T. In Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM 2012) : 20th Annual Meeting & Exhibition. Editors J.G. Pipe, G.E. Gold et al. - Berkeley, CA, USA : ISMRM, 2012. ISSN 1545-4428, p. 3317. CD-ROM.

6. JURÁŠ, Vladimír - PRESSL, C. - NOEBAUER-HUHMANN, I.M. - ZBYN, S. - SZOMOLANYI, P. - DOMAYER, S. - FROLLO, Ivan - TRATTNIG, S. Sodium MR imaging as a marker for achilles tendinopathy. In Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM 2012) : 20th Annual Meeting & Exhibition. Editors J.G. Pipe, G.E. Gold et al. - Berkeley, CA, USA : ISMRM, 2012. ISSN 1545-4428, p. 1461. CD-ROM.

2013

1. VALKOVIČ, Ladislav - UKROPCOVÁ, B. - CHMELÍK, M. - BALÁŽ, M. - BOGNER, W. - SCHMID, A.I. - FROLLO, Ivan - ZEMKOVÁ, E. - KLIMEŠ, I. - UKROPEC, J. - TRATTNIG, S. - KRŠŠÁK, M. Interrelation of 31P-MRS metabolism measurements in resting and exercised quadriceps muscle of overweight-to-obese sedentary individuals. In NMR in Biomedicine, 2013, vol. 26, no. 12, p. 1714-1722. ISSN 0952-3480. (3.446-IF2012)

2. VALKOVIČ, Ladislav - CHMELÍK, M. - KUKUROVÁ, I.J. - KRŠŠÁK, M. - GRUBER, S. - FROLLO, Ivan - TRATTNIG, S. - BOGNER, W. Time-resolved phosphorous magnetization transfer of the human calf muscle at 3 T and 7 T: A feasibility study. In European Journal of Radiology, 2013, vol. 82, no. 5, p. 745-751. ISSN 0720-048X. (2.512-IF2012)

3. CHMELÍK, M. - KUKUROVÁ, I.J. - GRUBER, S. - KRŠŠÁK, M. - VALKOVIČ, Ladislav - TRATTNIG, S. - BOGNER, W. Fully adiabatic 31P 2D-CSI with reduced chemical shift displacement error at 7 T - GOIA-1D-ISIS/2D-CSI. In Magnetic Resonance in Medicine, 2013, vol. 69, no. 5, p. 1233-1244. ISSN 0740-3194. (3.267-IF2012)

4. FRUEHWALD-PALLAMAR, J. - SZOMOLÁNYI, Pavol - FAKHRAI, N. - LUNZER, A. - WEBER, M. - THURNHER, M.M. - PALLAMAR, M. - TRATTNIG, S. - PRAYER, D. - NOEBAUER-HUHMANN, I.M. Parallel imaging of the cervical spine at 3T: Optimized trade-off between speed and image quality. In American Journal of Neuroradiology, 2012, vol. 33, no. 10, p. 1867-1874. ISSN 0195-6108. (3.167-IF2012)

5. JURÁŠ, Vladimír - APPRICH, S. - SZOMOLÁNYI, Pavol - BIERI, O. - DELIGIANNI, X. - TRATTNIG, S. Bi-exponential T2* analysis of healthy and diseased Achilles tendons: An in vivo preliminary magnetic resonance study and correlation with clinical score. In European Radiology, 2013, vol. 23, no. 10, p. 2814-2822. ISSN 0938-7994. (3.548-IF2012)

6. JURÁŠ, Vladimír - APPRICH, S. - SZOMOLÁNYI, Pavol - DOMAYER, S. - FROLLO, Ivan - TRATTNIG, S. Bi-exponential T2* analysis of meniscus. In MEASUREMENT 2013 : 9th International Conference on Measurement. Editors J. Maňka, M. Tyšler, V. Witkovský, I. Frollo. - Bratislava : Institute of Measurement Science, SAS, 2013, p. 129-132. ISBN 978-80-969-672-5-4

7. SZOMOLÁNYI, Pavol - SCHÖNBAUER, E. - JURÁŠ, Vladimír - ZBÝŇ, Š. - FROLLO, Ivan - TRATTNIG, S. MR T2 study of human knee cartilage using in-vivo compression device. In MEASUREMENT 2013 : 9th International Conference on Measurement. Editors J. Maňka, M. Tyšler, V. Witkovský, I. Frollo. - Bratislava : Institute of Measurement Science, SAS, 2013, p. 133-136. ISBN 978-80-969-672-5-4.

2014

1. JURÁŠ, Vladimír - APPRICH, S. - ZBÝŇ, Š. - ZAK, L. - DELIGIANNI, X. - SZOMOLÁNYI, P. - BIERI, O. - TRATTNIG, S. Quantitative MRI analysis of menisci using biexponential T2* fitting with a variable echo time sequence. In Magnetic Resonance in Medicine, 2014, vol. 71, no. 3, p. 1015-1023. ISSN 0740-3194. (3.398-IF2013)

2. RIEGLER, G. - DELIGIANNI, X. - JURÁŠ, Vladimír - ZBÝŇ, Š. - APPRICH, S. - SZOMOLÁNYI, P. - WEBER, M. - BIERI, O. - TRATTNIG, S. Quantitative T2*-mapping of the knee using a spoiled gradient echo sequence at 3 Tesla: Preliminary results. In Journal of Pharmacy and Pharmacology, 2014, vol. 2, no. 1, p. 59-69. ISSN 2328-2150.

3. JURÁŠ, Vladimír - APPRICH, S. - SZOMOLÁNYI, Pavol - ZBÝŇ, Š. - CHMELÍK, M. - TRATTNIG, S. Correlation of morphological score (VIMATS) with sodium MRI in patients with painful Achilles tendon. In Proceedings of the International Society for Magnetic Resonance in Medicine : Joint Annual Meeting ISMRM-ESMRMB. Editors D.K. Jones, Ch. Chung, M.A. Griswold, P. Jezzard, J.J. Neil. - Berkeley, CA, USA : ISMRM, 2014, Vol. 22, p. 1367. ISSN 1545-4428.

4. JURÁŠ, Vladimír - SZOMOLÁNYI, Pavol - HAGER, B. - CHMELIK, M. - ZBYN, S. - VOSSHENRICH, J. - TRATTNIG, S. Sodium, CEST and T2* of human Achilles tendon in subjects after ciprofloxacin treatment. In Proceedings of the International Society for Magnetic Resonance in Medicine : Joint Annual Meeting ISMRM-ESMRMB. Editors D.K. Jones, Ch. Chung, M.A. Griswold, P. Jezzard, J.J. Neil. - Berkeley, CA, USA : ISMRM, 2014, Vol. 22, p. 1229. ISSN 1545-4428.

5. JURÁŠ, Vladimír - MLYNÁRIK, V. - SZOMOLÁNYI, Pavol - CHMELÍK, M. - TRATTNIG, S. Practical requirements for Bi-exponential T2* fitting in Achilles tendon measured by variable echo time sequence. In Proceedings of the International Society for Magnetic Resonance in Medicine : Joint Annual Meeting ISMRM-ESMRMB. Editors D.K. Jones, Ch. Chung, M.A. Griswold, P. Jezzard, J.J. Neil. - Berkeley, CA, USA : ISMRM, 2014, Vol. 22, p. 1228. ISSN 1545-4428.

6. VALKOVIČ, Ladislav - CHMELÍK, M. - JUST KUKUROVÁ, I. - JAKUBOVÁ, M. - KIPFELSBERGER, M.Ch. - KRUMPOLEC, P. - TUŠEK JELENC, M. - BOGNER, W. - MEYERSPEER, M. - UKROPEC, J. - FROLLO, Ivan - UKROPCOVÁ, B. - TRATTNIG, S. - KRŠŠÁK, M. Depth-resolved surface coil MRS (DRESS)-localized dynamic 31P-MRS of the exercising human gastrocnemius muscle at 7 T. In NMR in Biomedicine, 2014, vol. 27, no. 11, p. 1346-1352. ISSN 0952-3480. (3.559-IF2013).

2015

1. JURÁŠ, Vladimír - WINHOFER, Y. - SZOMOLÁNYI, Pavol - VOSSHENRICH, J. - HAGER, B. - WOLF, P. - WEBER, M. - LUGER, A. - TRATTNIG, S. Multiparametric MR imaging depicts glycosaminoglycan change in the Achilles tendon during ciprofloxacin administration in healthy men: Initial observation. In Radiology, 2015, vol. 275, no. 3, p. 763-771. ISSN 0033-8419. (6.867-IF2014)
2. SCHOENBAUER, E. - SZOMOLÁNYI, Pavol - SHIOMI, T. - JURÁŠ, Vladimír - ZBÝŇ, Š. - ZAK, L. - WEBER, M. - TRATTNIG, S. Cartilage evaluation with biochemical MR imaging using in vivo Knee compression at 3T-comparison of patients after cartilage repair with healthy volunteers. In Journal of Biomechanics, 2015, vol. 48, no. 12, p. 3349-3355. ISSN 0021-9290. (2.751-IF2014)
3. ZBÝŇ, Š. - BRIX, M.O. - JURÁŠ, Vladimír - DOMAYER, S.E. - WALZER, S.M. - MLYNÁRIK, V. - APPRICH, S. - BUCKENMAIER, K. - WINDHAGER, R. - TRATTNIG, S. Sodium magnetic resonance imaging of ankle joint in cadaver specimens, volunteers, and patients after different cartilage repair techniques at 7 T : Initial results. In Investigative Radiology, 2015, vol. 50, no. 4, p. 246-254. ISSN 0020-9996. (4.437-IF2014)
4. GAJDOŠÍK, M. - CHADZYNSKI, G.L. - HANGEL, G. - MLYNÁRIK, V. - CHMELÍK, M. - VALKOVIČ, Ladislav - BOGNER, W. - POHMANN, R. - SCHEFFLER, K. - TRATTNIG, S. - KRŠŠÁK, M. Ultrashort-TE stimulated echo acquisition mode (STEAM) improves the quantification of lipids and fatty acid chain unsaturation in the human liver at 7T. In NMR in Biomedicine, 2015, vol. 28, no. 10, p. 1283-1293. ISSN 0952-3480. (3.044-IF2014)
5. CHMELÍK, M. - VALKOVIČ, Ladislav - WOLF, P. - BOGNER, W. - GAJDOŠÍK, M. - HALILBASIC, E. - GRUBER, S. - TRAUNER, M. - KREBS, M. - TRATTNIG, S. - KRŠŠÁK, M. Phosphatidylcholine contributes to in vivo 31P MRS signal from the human liver. In European Radiology, 2015, vol. 25, no. 7, p. 2059-2066. ISSN 0938-7994. (4.014-IF2014)
6. SCHOENBAUER, E. - SZOMOLÁNYI, Pavol - SHIOMI, T. - JURÁŠ, Vladimír - ZBÝŇ, Š. - ZAK, L. - WEBER, M. - TRATTNIG, S. Cartilage evaluation with biochemical MR imaging using in vivo Knee compression at 3T-comparison of patients after cartilage repair with healthy volunteers. In Journal of Biomechanics, 2015, vol. 48, no. 12, p. 3349-3355. ISSN 0021-9290. (2.751-IF2014)

2016

1. JURÁŠ, Vladimír - ZBÝŇ, Š. - MLYNÁRIK, V. - SZOMOLÁNYI, Pavol - HAGER, B. - BAER, P. - FROLLO, Ivan - TRATTNIG, S. The compositional difference between ankle and knee cartilage demonstrated by T2 mapping at 7 Tesla MR. In European Journal of Radiology, 2016, vol. 85, no. 4, p. 771-777. ISSN 0720-048X. (2.593-IF2015)

2.  KUKUROVÁ, I.J. - VALKOVIČ, Ladislav - UKROPEC, J. - DE COURTEN, B. - CHMELÍK, M. - UKROPCOVÁ, B. - TRATTNIG, S. - KRŠŠÁK, M. Improved spectral resolution and high reliability of in vivo 1H MRS at 7 T allow the characterization of the effect of acute exercise on carnosine in skeletal muscle. In NMR in Biomedicine, 2016, vol. 29, no. 1, p. 24-32. ISSN 0952-3480. (2.983-IF2015)

3.  SCHMID, A.I. - MEYERSPEER, M. - ROBINSON, S.D. - GOLUCH, S. - WOLZT, M. - FIEDLER, G.B. - BOGNER, W. - LAISTLER, E. - KRŠŠÁK, M. - MOSER, E. - TRATTNIG, S. - VALKOVIČ, Ladislav. Dynamic PCr and pH imaging of human calf muscles during exercise and recovery using 31P gradient-Echo MRI at 7 Tesla. In Magnetic Resonance in Medicine, 2016, vol. 75, no. 6, p. 2324-2331. ISSN 0740-3194. (3.782-IF2015)

4.  TRATTNIG, S. - BOGNER, W. - GRUBER, S. - SZOMOLÁNYI, Pavol - JURÁŠ, Vladimír - ROBINSON, S. - ZBÝŇ, Š. - HANEDER, S. Clinical applications at ultrahigh field (7T). Where does it make the difference? In NMR in Biomedicine, 2016, vol. 29, no. 9, p. 1316-1334. ISSN 0952-3480. (2.983 -IF2015)

5.  VALKOVIČ, Ladislav - CHMELÍK, M. - MEYERSPEER, M. - GAGOSKI, B. - RODGERS, C.T. - KRŠŠÁK, M. - ANDRONESI, O.C. - TRATTNIG, S. - BOGNER, W. Dynamic 31P -MRSI using spiral spectroscopic imaging can map mitochondrial capacity in muscles of the human calf during plantar flexion exercise at 7 T. In NMR in Biomedicine, 2016, vol. 29, no. 12, p. 1825-1834. ISSN 0952-3480. (2.983 -IF2015)

6.  VALKOVIČ, Ladislav - CHMELÍK, M. - UKROPCOVÁ, B. - HECKMANN, T. - BOGNER, W. - FROLLO, Ivan - TSCHAN, H. - KREBS, M. - BACHL, N. - UKROPEC, J. - TRATTNIG S. - KRŠŠÁK, M. Skeletal muscle alkaline Pi pool is decreased in overweight-to-obese sedentary subjects and relates to mitochondrial capacity and phosphodiester content. In Scientific Reports, 2016, vol. 6, p. 20087. ISSN 2045-2322. (5.228-IF2015)