- Research of static magnetic field deformation due to the presence of magnetic nanoparticles using imaging methods based on magnetic resonance principles
- Class of the logarithmic Lambert W x F random variables and their applications
- Superconducting model of magnetic impurities in the diamagnetic matrix
- New methods of non-destructive volume analysis of rocks and minerals using X-ray microtomography
Result 1: Research of static magnetic field deformation due to the presence of magnetic nanoparticles using imaging methods based on magnetic resonance principles
Projects: VEGA 2/0013/14 a APVV-0513-10 (Institute of Measurement Science SAS)
Authors: I. Frollo, O. Štrbák, A. Krafčík, D. Gogola
Magnetic nanoparticles are widely used as a contrast agent in magnetic resonance imaging (MRI). Nanoparticles as contrast agents possess a magnetic moment which generates local inhomogeneities in the static magnetic field of the MR scanner. The goal of this study was to investigate the influence of the arrangement of magnetic nanoparticles on the final image contrast during MRI.
The magnetic field distortions of the near surroundings of the groups of magnetic nanoparticles Fe3O4, which are regarded as small magnetic dipoles were analyzed. The influence of saline and glucose molecules to contrast properties of clinically used MRI contrast agents were investigated. Because in general, circular samples were investigated as objects for imaging based on magnetic resonance, detailed mathematical models were developed. Resultant simulations were experimentally verified. The computer-aided analysis of magnetic nanoparticles deposition caused by magnetic field was carried out.
The methods find applications in research of physiologic and pathologic changes of metabolism in biological objects and could be used mainly in the clinical practice.
a) b)
Fig 1. a) Contour plot of the magnetic field of four nanoparticles. The centre-to-centre distance of nanoparticles was 50 nm. Diameter of contour with value of magnetic field 0.02 T is 160.3 nm.
b) Mathematical model of the distribution of homogeneous magnetic field B0, lines of force affected by 2 concentric cylinders with relative permeabilities: μ1=2 and μ2=3, μ0 is an environment permeability.
Publications:
- FROLLO, Ivan - KRAFČÍK, Andrej - ANDRIS, Peter - PŘIBIL, Jiří -
DERMEK, Tomáš. Circular Samples as Objects for Magnetic Resonance
Imaging - Mathematical Simulation, Experimental Results. In Measurement
Science Review, Volume 15, No. 6, 2015, p. 313-318. ISSN 1335 - 8871.
(0.989-IF2014)
- ŠTRBÁK, Oliver - MASÁROVÁ, Marta - GOGOLA, Daniel - SZOMOLÁNYI,
Pavol - FROLLO, Ivan. Influence of saline and glucose molecules to
contrast properties of clinically used MRI contrast agents. In
Measurement, 2015, vol. 69, p. 109-114. ISSN 0263-2241. (1.484-IF2014)
- KRAFČÍK, Andrej - BABINEC, P. - FROLLO, Ivan. Computational
analysis of magnetic field induced deposition of magnetic particles in
lung alveolus in comparison to deposition produced with viscous drag and
gravitational force. In Journal of Magnetism and Magnetic Materials,
2015, vol. 380, p. 46-53. ISSN 0304-8853. (1.970-IF2014)
- GOGOLA, Daniel - ŠTRBÁK, Oliver - KRAFČÍK, Andrej - ŠKRÁTEK, Martin
- FROLLO, Ivan. Magnetic resonance imaging of the static magnetic field
distortion caused by magnetic nanoparticles: Simulation and
experimental verification. In Journal of Magnetism and Magnetic
Materials, 2015, vol. 380, p. 261-265. ISSN 0304-8853. (1.970-IF2014)
Result 2: Class of the logarithmic Lambert W x F random variables and their applications
Projects: APVV-0096-10, VEGA 1/0043/13, VEGA 2/0047/15 (Institute of Measurement Science SAS)
Authors: V. Witkovský (Institute of Measurement Science SAS)
Co-authors: G. Wimmer, T. Duby
We have defined a new class of log-linearly transformed random variables, the class of logarithmic Lambert W x F random variables. We have studied in detail the properties and the probability distribution of these random variables. The class of the log-Lambert W x F random variable is of particular interest, because the Lambert W function (special multivalued mathematical function known as the omega function or product logarithm) allows to calculate the exact probability distribution of the log-linearly transformed random variables with a known distribution F. An important role in this class belongs to be log-linearly transformed random variables with Chi-squared distribution. In particular, the probability distribution of the likelihood ratio test statistic in models with gaussian errors of measurement belongs to this type of probability distributions. In this work we have extensively characterized basic properties of that distribution, including the characteristic function of the distribution and its basic moments. Knowledge of the characteristic function allows to calculate the explicit distribution of linear combinations of such random variables, which is important for determining the critical values of the test statistics in linear models with normal (gaussian) errors.
Fig. 1. The exact probability distribution of the likelihood ratio test statistic (LRT) to test hypotheses about the parameters of the linear mixed model for three different versions of the null hypothesis H0 and its comparison with the asymptotic distribution (shown by the dotted curve), which is often used as an approximation of the actual distribution under the null hypothesis. In this example, the true hypothesis is H01, and thus the exact distribution of the LRT statistics is shown in solid blue line.
Publications:
- WITKOVSKÝ, Viktor - WIMMER, G. - DUBY, T. Logarithmic Lambert W × F
random variables for the family of chi-squared distributions and their
applications. In Statistics & Probability Letters, 2015, vol. 96, p.
223-231. ISSN 0167-7152. (0.595-IF2014) (CC publikácia)
- WITKOVSKÝ, Viktor - WIMMER, G. - ĎURIŠ, S. On statistical methods
for common mean and reference confidence intervals in interlaboratory
comparisons for temperature. In International Journal of Thermophysics,
2015, vol. 36, no. 8, p. 2150-2171. ISSN 0195-928X. (0.963-IF2014) (CC
publikácia)
- WITKOVSKÝ, Viktor. Numerical inversion of a characteristic
function: An alternative tool to form the probability distribution of
output quantity in linear measurement models. In IMEKO: XXI World
Congress. Editor J. Holub. Czech Technical University in Prague, Faculty
of Electrical Engineering, Department of Measurement, 2015. ISBN
978-80-01-05793-3.
Result 3: Supravodivý model magnetických prímesí v diamagnetickej matrici
Projects: APVV-0125-11, ASFEU projekt 26240220073 (Kompetenčné
centrum pre nové materiály, pokročilé technológie a energetiku), ASFEU
projekt 26240120019 (CENTE II).
Authors: A. Cigáň, A. Dvurečenskij, M. Škrátek, M. Majerová, P. Billik, J. Maňka
V oblasti vývoja magnetických nanokvapalín a
nanočastíc pre priemyselné a biomedicínske aplikácie, ako je napr.
čistenie odpadových vôd od ťažkých kovových iónov, MRI diagnostika,
cielený transport liečiv, alebo liečba nádorových ochorení hypertermiou,
je potrebné poznať ich magnetické vlastnosti, ktoré predstavujú jednu z
ich projektovaných funkcionalít. Posledné je zvlášť významné pre
nanočastice malých rozmerov alebo kompozitné nanočastice, skladajúce sa z
jadra a viacerých obalových vrstiev, ktoré sú nositeľmi ich
multifunkčných vlastností. Z pohľadu magnetických vlastnosti je potrebné
riešiť otázku vzájomného ovplyvňovania jadra, jeho povrchovej vrstvy a
jednotlivých obalových vrstiev na výsledné vlastnosti nanočastíc a v
prípade magnetických nanokvapalín aj vzájomný vplyv kvapalného média,
ktoré najčastejšie je diamagnetické a tuhých magnetických nanočastíc. V
našich prácach sme študovali vplyv dopovania vysokoteplotného
supravodiča Eu-123 ruténiom. Supravodič je model ideálnej diamagnetickej
matrice a dopovanie s Ru vedie k tvorbe Ba3EuRu2O9 fázy obsahujúcej
magnetické diméry Ru2O9. Získané výsledky naznačujú novú možnú cestu
štúdia vzájomného ovplyvňovania sa diamagnetických a magnetických médií s
využitím supravodičov a teploty ako kľúča na vypnutie ich
diamagnetických vlastností.
Publications:
- DVUREČENSKIJ, Andrej - CIGÁŇ, Alexander - BYSTRICKÝ, Roman -
ŠKRÁTEK, Martin - BILLIK, Peter - MAJEROVÁ, Melinda - MAŇKA, Ján.
Magnetic studies of EuBa2Cu3-xRuxO7-δ compounds. In Acta Physica
Polonica A, 2015, vol. 127, no. 2, p. 300-302. ISSN 0587-4246.
(0.530-IF2014)
- ŠKRÁTEK, Martin - CIGÁŇ, Alexander - DVUREČENSKIJ, Andrej -
MAJEROVÁ, Melinda - BYSTRICKÝ, Roman - BILLIK, Peter - MAŇKA, Ján.
Effects of Ru addition on the superconducting properties of the Eu-123
system. In Acta Physica Polonica A, 2015, vol. 127, no. 2, p. 225-227.
ISSN 0587-4246. (0.530-IF2014)
Result 4: New methods of non-destructive volume analysis of rocks and minerals using X-ray microtomography
Project: VEGA 2/0126/13 (Institute of Measurement Science SAS)
Author: M. Hain
Microtomographic methods used for non-destructive volume analysis of rocks and minerals in geology and mineralogy were developed and applied. In the frame of the methodology proposal, the microtomographic measurement conditions for these objects were optimized, including choice of optimal accelerating voltage and current of X-ray tube, signal accumulation time, number of repeated measurements, the relaxation time of the detector, choice of material of the targets and the number of X-ray projections. In the subsequent processing and visualization of results of microtomographic measurements, the methodology of 3D visualization of geological microstructures and defects with the application of methods for data filtering, rendering and image segmentation was elaborated. The results were applied in the collaboration with Dr. Ďurmeková and Dr. Ružička from the Faculty of Natural Sciences, Comenius University at the microtomographic analysis of a series of marble samples exposed to prolonged exposure of adverse chemical and physical agents.
Fig. 1. Microtomographic visualization of marble samples exposed to a prolonged exposure of adverse chemical and physical agents
Publication:
-
DURMEKOVÁ, T. - RUŽIČKA, P. - HAIN, Miroslav - ČAPLOVIČOVÁ, M.
Changes in marble quality after sodium sulphate crystallization and
long-lasting freeze-thaw testing. In Engineering Geology for Society and
Territory - Volume 5 : Urban Geology, Sustainable Planning and
Landscape Exploitation. Springer, 2015. ISBN 978-3-319-09047-4, p.
237-241.
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